Brainiac: Science Abuse is a British reality show that aired on Sky One from 13 November 2003 to 30 March 2008. During each episode of the show, numerous experiments are carried out to whether common conceptions are true or simply to create impressive explosions. The show centres on the three core branches of science for the key stages in British education: chemistry, physics and to a lesser extent, biology. The experimenters on the show are referred to as "Brainiacs", and each episode usually finishes with the destruction of a caravan. The show is produced by Granada Productions and is broadcast in Ireland and the United Kingdom on Sky Digital. The original presenters were Richard Hammond and Jon Tickle, then ed in the second series by Charlotte Hudson. Hammond left after the fourth, and was replaced by Vic Reeves and Hudson left after the fifth, and was replaced by Thaila Zucchi. In July 2008, after the sixth series had finished, Sky announced they had cancelled the show due to the sixth series' low ratings.